CEA, Carcinoembryonic Antigen, CD66eCatalog number: CD66E2-5
CEA is frequently used as a differential marker for adenocarcinoma and mesothelioma. Carcinoembryonal Antigen (CEA) is a high molecular glycoprotein (180 kD), which is detected in foetal colon and in colorectal carcinoma. It is a component of the s. c. glycocalyx of the embryonal endodermal epithelium. In normal adult colon it is found in very small amount only. In colorectal carcinoma and metastases of intestinal carcinoma however, it is strongly exprimed. Human CEA.
Immunogen: Colon carcinoma extract from human tissue
Purified antibody in PBS pH 7.3, contains BSA and sodium azide (0,09%)
Purification Method: Purified antibody in PBS pH 7.3, contains BSA and sodium azide (0,09%)
Secondary Reagents: We recommend the use of BIOLOGO's Universal Staining System DAB (Art. No. DA005) or AEC (Art.-No. AE005).
Concentration: 5 µg/ml
Species Reactivity: Human
Incubation Time: 60 min at RT
Working Concentration: (RTU)
Pre-Treatment: Improvement of staining with Unmasking Fluid G (Art. No. DE007) or Unmasking Fluid C (Art. No. DE000)
Positive Control: Colon carcinoma
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.
1. Sheahan K., O'Brien M.J., Burke B., Dervan P.A., O'Keane J.C., Gottlieb L.S. et al. (1990) Differential reactivities of carcinoembryonic antigen (CEA) and CEA-related monoclonal and polyclonal antibodies in common epithelial malignancies. Am. J. Clin. Pathol. 94; 157-164. . 2. Ghosh A.K., Gatter K.C., Dunnill M.S., Mason D.Y. (1987) Immunohistochemical staining of reactive Mesothelium, mesothelioma, and Lung carcinoma with a panel of monoclonal antibodies. J. Clin. Pathol. 40; 19-25. 3. Nap M., Hammarström M.-L., Börmer O., Hammarström S., Wagener C., Handt S., et al. (1992) Cancer Res. 52; 23-39
Database Name: UniProt
Accession Number: P06731
Safety Datasheet(s) for this product: