Mouse anti Human p107Catalog number: N100M
P107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors.
Synonyms: p107; Retinoblastoma-like protein 1; PRB1; 107 kda retinoblastoma-associated protein
The immunogen used to immunize the mice was a recombinant GST protein coupled to the N-terminus of p107.
KAB6 recognizes both the phosphorylated and unphosphorylated forms of p107 at a MW of 107kDa.
Product Form: Unconjugated
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purification Method: Protein A/G Chromatography
Concentration: See vial for concentration
Western Blots at 1:1000
Functional Analysis: Western Blot
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Product Stability: See expiration date on vial
Shipping Conditions: Ship at ambient temperature
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.
Database Name: UniProt
Accession Number: P28749 (Human) Q64701 (Mouse)
Species Accession: Human
Safety Datasheet(s) for this product: