Mouse anti Human p130Catalog number: N105M
P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa.
Synonyms: p130; Retinoblastoma-like protein 2; RBR-2; PRB2
The immunogen used was a recombinant protein to the N terminus of p130.
Monoclonal antibody provided as solution in phosphate buffered saline with 0.08% sodium azide
Product Form: Unconjugated
Purification Method: Protein A/G Chromatography
Concentration: See vial for concentration
Western Blots at 1:1000
Functional Analysis: Western Blotting
Positive Control: This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa. And is suitable for use in western blot with his- tagged or GST tagged proteins.
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Product Stability: See expiration date on vial
Shipping Conditions: Ship at ambient temperature
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.
Database Name: UniProt
Accession Number: Q08999 (Human)Q64700 (Mouse)O55081 (Rat)
Species Accession: Human, Rat, Mouse
Safety Datasheet(s) for this product: